A well-known source of evidence for evolution is presented in the NIH’s National Library of Medicine’s book chapter Evidence for Evolution (NCBI, 2014). 1 This resource compiles six major lines of evidence frequently cited by evolutionary biologists, spanning observed microevolution, biogeography, comparative anatomy, the fossil record, classification, and molecular genetics. Proponents of evolution often present these categories as a comprehensive and irrefutable case for the theory, leveraging the authority of scientific consensus and the breadth of examples to assert its validity.
However, a critical examination through a young earth creationist (YEC) lens reveals that these lines of evidence often rely on untested assumptions, incomplete data interpretations, and ambiguous findings. Each category can be deconstructed to highlight significant limitations in the evolutionary narrative, while the YEC model provides a more coherent explanation, grounded in observable biological limits, functional design, and a historical framework consistent with a global Flood.
1. Observed Small-Scale Evolution (Microevolution)
Evolutionary Claim: Adaptive Mutations Drive Observable Change
Evolutionists argue that small-scale evolutionary changes, or microevolution, are directly observable in phenomena such as antibiotic resistance in bacteria, pesticide resistance in insects, and selective breeding in domesticated species. These examples demonstrate how genetic mutations and natural selection can lead to adaptive changes within populations over short timescales, providing a foundation for extrapolating larger evolutionary processes over millions of years.
For instance, the development of antibiotic-resistant strains of bacteria like Escherichia coli is cited as evidence of evolution in action, suggesting that similar mechanisms could drive the emergence of new species or complex traits over time. 2
YEC Response: Microevolution Reflects Limited Variation, Not Novelty
Young earth creationists acknowledge microevolution as variation within created kinds, but argue it does not support the broader claims of macroevolution. Observed changes, such as antibiotic resistance, typically involve the loss or modification of existing genetic information rather than the generation of new, complex functions.
For example, antibiotic resistance in E. coli often results from mutations that disable porin channels (e.g., OmpF or OmpC), preventing antibiotics from entering the cell. This is a degenerative trade-off, reducing cellular efficiency for survival, not an example of innovative genetic gain. 3
A prominent example often cited by evolutionists is the Lenski long-term evolution experiment, which reported E. coli evolving the ability to metabolize citrate under aerobic conditions, supposedly demonstrating novel trait acquisition. However, this adaptation involved the loss of regulatory control, allowing a pre-existing anaerobic citrate metabolism pathway to function inefficiently under aerobic conditions. This process, driven by a duplication and rearrangement of the citT gene, resulted in wasteful citrate uptake and did not introduce new genetic information or functional complexity. Instead, it reflects a degenerative modification, consistent with YEC predictions of genomic decay within created kinds rather than upward evolutionary innovation. 4 5 6 7 8 9
2. Biogeography
Evolutionary Claim: Species Distribution Reflects Ancestral Divergence
Biogeography studies the distribution of species across geographic regions, with evolutionists arguing that patterns—such as the predominance of marsupials in Australia or the diverse finch species of the Galápagos Islands—reflect descent from common ancestors shaped by geographic isolation and environmental pressures. These distributions are interpreted as evidence of speciation driven by adaptation to distinct ecological niches over long timescales. 10
YEC Response: Post-Flood Dispersal and Rapid Adaptation
YEC posits that biogeographic patterns are better explained by rapid post-Flood migration and diversification within created kinds, facilitated by pre-existing genetic variability.
The breakup of a post-Flood supercontinent (akin to Pangea) allowed animals to disperse rapidly, with subsequent environmental pressures triggering adaptive changes within the genetic boundaries of created kinds.
For instance, the variation in Galápagos finch beak morphology results from regulatory gene changes (e.g., BMP4 or ALX1), which modulate the expression of existing genetic programs rather than creating novel genetic information. These rapid adaptations align with a YEC timeline of thousands, not millions, of years. 11
3. Comparative Anatomy and Vestigial Structures
Evolutionary Claim: Homology and Vestigial Organs Indicate Common Ancestry
Evolutionists argue that homologous structures (e.g., the forelimbs of humans, bats, and whales) and vestigial organs (e.g., the human appendix or whale pelvic bones) provide evidence of shared ancestry. Homologies suggest a common evolutionary origin, while vestigial structures are interpreted as remnants of organs that were functional in ancestors but have lost their primary function through evolutionary reduction. 12
YEC Response: Common Design Explains Similarity, Functionality Persists
YEC counters that anatomical similarities reflect common design principles, not common ancestry.
Convergent evolution—where unrelated species like octopuses and humans develop similar camera-like eyes, or bats and birds develop wings—undermines the assumption that similarity equates to relatedness.
Alleged vestigial structures often retain critical functions: the human appendix serves as a reservoir for beneficial gut bacteria, and whale pelvic bones anchor reproductive muscles, indicating purposeful design rather than evolutionary relics. These observations align with a YEC view of created kinds with built-in adaptability, not gradual evolutionary transitions. 13
4. Fossil Record and Transitional Forms
Evolutionary Claim: Fossils Show Gradual Progression
The fossil record is cited as evidence of a chronological progression from simple to complex organisms, with transitional forms like Tiktaalik (a fish-tetrapod intermediate) illustrating evolutionary transitions. Geological strata are interpreted as a record of millions of years, capturing the gradual emergence of new forms through natural selection and mutation. 14
YEC Response: Flood Geology Explains Fossil Patterns
YEC argues that the fossil record is better explained by rapid burial during a global Flood, consistent with catastrophic sedimentation.
Polystrate fossils, such as trees spanning multiple sedimentary layers, and marine fossils atop mountain ranges like the Himalayas, support rapid, large-scale deposition rather than slow accumulation over millions of years.
Tiktaalik and similar fossils exhibit mosaic traits—combinations of fish and tetrapod features—but lack evidence of the stepwise genetic or developmental changes required for evolutionary transitions. These fossils fit a YEC model of created kinds with fixed boundaries, buried in a sequence reflecting ecological zones during a global catastrophe, not a gradual evolutionary timeline. 15
5. Classification and Phylogenetics
Evolutionary Claim: Taxonomic Hierarchies Reflect Ancestry
Evolutionists assert that nested taxonomic hierarchies and genetic similarities, as depicted in phylogenetic trees, reflect a universal tree of life rooted in common ancestry.
Shared genetic sequences across species are interpreted as evidence of divergence from shared ancestors, with classification systems organizing this evolutionary history. 16
YEC Response: Subjective Taxonomies and Designed Similarities
YEC views taxonomic hierarchies as human-imposed classifications that do not necessarily reflect objective biological realities. Phylogenetic trees are frequently revised as new genetic data disrupt expected relationships, resulting in “bushes” or “webs” rather than clear trees. Genetic similarities, such as in cytochrome c, often involve highly conserved genes essential for life, suggesting design constraints rather than evolutionary heritage. Phenomena like horizontal gene transfer and convergent evolution further complicate evolutionary inferences, while a YEC model of created kinds with limited variation accounts for genetic similarities and taxonomic patterns without requiring universal common ancestry. 17
6. Genetics and Molecular Biology
Evolutionary Claim: Shared Genetic Features and Junk DNA Support Common Descent
Evolutionists argue that shared genetic features, such as endogenous retroviruses (ERVs) and pseudogenes, provide strong evidence for common descent. Identical ERV insertion sites across species and non-functional pseudogenes, like the human β-globin pseudogene, are interpreted as inherited remnants of evolutionary history. 18
Additionally, evolutionary theory predicts a high proportion of non-functional “junk” DNA, as mutational load—based on mutation rates of approximately 10^-8 per base pair per generation—suggests that only about 20% of the genome can remain functional without accumulating deleterious mutations over millions of years, with the remainder being non-coding or vestigial sequences resulting from evolutionary processes. 19
YEC Response: Functional Design and Genomic Decay, Not Evolutionary Relics
Young Earth Creationism (YEC) argues that genetic features like endogenous retroviruses (ERVs) and pseudogenes reflect purposeful design or post-Fall genomic decay, not evolutionary relics. Evolution predicts a high proportion of non-functional “junk” DNA, as mutational load—based on known mutation rates of approximately 10^-8 per base pair per generation—limits functional DNA to about 20% of the genome to avoid deleterious accumulation of mutations. 19 However, recent studies reveal that up to 80% of the human genome exhibits biochemical functionality, far exceeding evolutionary expectations, with functionality now measured beyond direct transcription to include regulatory roles, chromatin structure, and non-coding RNA activity. 20
For example, the human β-globin pseudogene, once deemed “junk,” has regulatory roles in gene expression, while ERVs may insert at genomic hotspots due to functional mechanisms, not shared ancestry. Non-functional genes, often cited as evolutionary remnants, resemble highly specific, broken functional genes—consistent with a designed genome undergoing degradation rather than random, non-functional sequences accumulating over millions of years. Genetic similarities across species are better explained by common design for shared biological functions, not divergence from a common ancestor. The absence of clear evidence for the generation of new genetic information aligns with YEC predictions of fixed created kinds undergoing limited variation and degeneration, not macroevolutionary change. 21
Conclusion
The six lines of evidence presented by the NCBI for evolution hinge on speculative assumptions about deep time, universal common ancestry, and the unproven generation of novel genetic information. When subjected to rigorous scrutiny through a Young Earth Creationist (YEC) lens, these claims unravel, exposing critical flaws such as misinterpretations of data, reliance on unobserved mechanisms, and a consistent failure to account for the complexity and functionality of biological systems. Evolutionary theory’s dependence on ad hoc explanations, such as convergent evolution or horizontal gene transfer, reveals its fragility and inability to cohesively explain the observed evidence without constant revision.
In stark contrast, the YEC framework provides a compelling and scientifically robust alternative, decisively accounting for biological variation, fossil distributions, and genetic patterns through the lens of created kinds, rapid post-Flood adaptation, and a global catastrophic Flood. This model not only aligns seamlessly with observable data—such as rapid sedimentation, polystrate fossils, and the pervasive functionality of so-called “junk” DNA—but also offers predictive power that evolution lacks, consistently anticipating limits to genetic variation and the preservation of designed functionality. Grounded in the authoritative historical narrative of Scripture, YEC stands as a superior interpretive paradigm, harmonizing scientific observations with the biblical account of creation and the Flood, and confidently challenging the evolutionary narrative as an inadequate explanation for life’s complexity and diversity.
- Evidence for Evolution (NCBI, 2014)[↩]
- Antibiotic Resistance and Evolution (ASM, 2010)[↩]
- Antibiotic Resistance: Evolution or Devolution? (Creation Ministries International, 2016)[↩]
- Lenski’s Experiment: Citrate-Digesting E. coli? (Answers in Genesis, 2018)[↩]
- Long-Term Experimental Evolution in Escherichia coli. I. Adaptation and Divergence During 2,000 Generations (The American Naturalist, 1991)[↩]
- Dynamics of Adaptation and Diversification: A 10,000-Generation Experiment with Bacterial Populations (Proceedings of the National Academy of Sciences, 1994)[↩]
- Long-Term Experimental Evolution in Escherichia coli. XII. DNA Topology as a Key Target of Selection (Genetics, 2005)[↩]
- Genome Evolution and Adaptation in a Long-Term Experiment with Escherichia coli (Nature, 2009)[↩]
- Genomic Analysis of a Key Innovation in an Experimental Escherichia coli Population (Nature, 2012)[↩]
- Biogeography: Where Life Lives (UC Berkeley, 2019)[↩]
- Galápagos Finches: Showing Variation Within a Kind (Answers in Genesis, 2020)[↩]
- Evidence for Evolution: Homology and Vestigial Structures (Khan Academy, 2021)[↩]
- Vestigial Organs Revisited (Creation Ministries International, 2019)[↩]
- Tiktaalik roseae: A Fish-Tetrapod Transition (Nature, 2006)[↩]
- Tiktaalik and the Fishy Story of Walking Fish (Answers in Genesis, 2017)[↩]
- Reading a Phylogenetic Tree (Nature Education, 2010)[↩]
- Phylogenetic Trees: A YEC Perspective (Creation Ministries International, 2022)[↩]
- Endogenous Retroviruses and Evolution (PNAS, 2000)[↩]
- Mutational Load and the Functional Fraction of the Human Genome (Genetics, 2010)[↩][↩]
- An Integrated Encyclopedia of DNA Elements in the Human Genome (Nature, 2012)[↩]
- Pseudogenes: Functional or Broken Genes? (Answers in Genesis, 2021)[↩]